Package: bhm 1.19

bhm: Biomarker Threshold Models

Contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.

Authors:Bingshu E. Chen

bhm_1.19.tar.gz
bhm_1.19.zip(r-4.5)bhm_1.19.zip(r-4.4)bhm_1.19.zip(r-4.3)
bhm_1.19.tgz(r-4.4-any)bhm_1.19.tgz(r-4.3-any)
bhm_1.19.tar.gz(r-4.5-noble)bhm_1.19.tar.gz(r-4.4-noble)
bhm_1.19.tgz(r-4.4-emscripten)bhm_1.19.tgz(r-4.3-emscripten)
bhm.pdf |bhm.html
bhm/json (API)

# Install 'bhm' in R:
install.packages('bhm', repos = c('https://statapps.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/statapps/bhm/issues

Datasets:

On CRAN:

77 exports 1 stars 1.12 score 31 dependencies 9 scripts 380 downloads

Last updated 1 months agofrom:4c990823a3. Checks:OK: 1 WARNING: 6. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 14 2024
R-4.5-winWARNINGSep 14 2024
R-4.5-linuxWARNINGSep 14 2024
R-4.4-winWARNINGSep 14 2024
R-4.4-macWARNINGSep 14 2024
R-4.3-winWARNINGSep 14 2024
R-4.3-macWARNINGSep 14 2024

Exports:bhmbhm.defaultbhm.formulabhmControlbhmFitbhmGibbsbrmbrm.defaultbrm.formulacoxScoreHessdpicexpgendat.glmgendat.survggkmglmpLRTglmpLRT.defaultglmpLRT.formulahpicexpHpicexpllmllm.defaultllm.formulamplmpl.formulamplFitmultiRootnumHessiannumJacobiannumScorepicfitpicregpIndexpIndex.defaultpIndex.formulapIndexControlpIndexFitpIndexLocalpIndexThresholdplot.bhmplot.brmplot.glmpLRTplot.llmplot.pIndexplot.resbootplot.residuals.brmplot.rmscbppicexpprint.bhmprint.brmprint.glmpLRTprint.llmprint.mplprint.picregprint.pIndexprint.resbootprint.rmscbprint.summary.bhmprint.summary.brmprolikFitqpicexpresbootresboot.defaultresboot.formularesiduals.brmrmscbrmscb.defaultrmscb.formularmsControlrpicexpsummary.bhmsummary.brmsummary.glmpLRTsummary.picregsummary.rmscbthm.fitthm.likx.cdf

Dependencies:clicodacolorspacefansifarverggplot2gluegridExtragtableisobandlabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellnlmepillarpkgconfigR6RColorBrewerrlangscalessurvivaltibbleutf8vctrsviridisLitewithr

Readme and manuals

Help Manual

Help pageTopics
An R package for the biomarker threshold modelsbhm-package bhm-doc
Fitting Biomarker Threshold Modelsbhm bhm.default bhm.formula bhmFit bhmGibbs prolikFit summary.bhm thm.fit thm.lik x.cdf
Auxiliary function for bhm fittingbhmControl prolikControl
Fitting Biomarker Continuous Threshold Modelsbrm brm.default brm.formula residuals.brm summary.brm
datasetdata gendat.glm gendat.surv
Creates a Kaplan-Meier plot with at risk tables belowggkm
Penalized likelihood ratio test for the generalized linear models.glmpLRT glmpLRT.default glmpLRT.formula plot.glmpLRT print.glmpLRT summary.glmpLRT
Fit an L-shape linear modelllm llm.default llm.formula plot.llm print.llm
Joint models for clustered data with binary and survival outcomes.mpl mpl.formula mplFit
m-Dimensional Root (Zero) FindingmultiRoot
Calculate Hessian or Information MatrixnumHessian
Calculate the Score / Jacobian FunctionnumJacobian numScore
Probability Index for Survival Time DifferencepIndex pIndex.default pIndex.formula pIndexFit pIndexLocal pIndexThreshold
Auxiliary function for pIndex fittingpIndexControl
Plot a fitted biomarker threhold modelplot.bhm plot.brm plot.pIndex plot.resboot plot.residuals.brm
print a fitted object or a summary of fitted objectprint.bhm print.brm print.mpl print.picreg print.pIndex print.resboot print.summary.bhm print.summary.brm
Rresidual Bootstrap Test (RBT) for treatment-biomarker interactionresboot resboot.default resboot.formula
Fitting Restricted Mean Survival Time Models with a Continuous Biomarkerplot.rmscb print.rmscb rmscb rmscb.default rmscb.formula rmsControl summary.rmscb
The Piecewise Exponential Distributiondpicexp Hpicexp hpicexp picfit picreg ppicexp qpicexp rpicexp summary.picreg