Package: bhm 1.20

bhm: Biomarker Threshold Models

Contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.

Authors:Bingshu E. Chen [aut, cre]

bhm_1.20.tar.gz
bhm_1.20.zip(r-4.7-any)bhm_1.20.zip(r-4.6-any)bhm_1.20.zip(r-4.5-any)
bhm_1.20.tgz(r-4.6-any)bhm_1.20.tgz(r-4.5-any)
bhm_1.20.tar.gz(r-4.7-any)bhm_1.20.tar.gz(r-4.6-any)
bhm_1.20.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
bhm/json (API)

# Install 'bhm' in R:
install.packages('bhm', repos = c('https://statapps.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/statapps/bhm/issues

Datasets:

On CRAN:

Conda:

3.00 score 2 stars 9 scripts 407 downloads 83 exports 25 dependencies

Last updated from:a46cf87526. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develOK116
source / vignettesOK140
linux-releaseOK131
macos-releaseOK140
macos-oldrelOK99
windows-develOK73
windows-releaseOK86
windows-oldrelOK101
wasm-releaseOK79

Exports:arnsarsbhmbhm.defaultbhm.formulabhmControlbhmFitbhmGibbsbrmbrm.defaultbrm.formulacoxpLRTcoxpLRT.defaultcoxpLRT.formulacoxpLRTcvPredErrdpicexpgendat.glmgendat.survggkmglmpLRTglmpLRT.defaultglmpLRT.formulahpicexpHpicexpllmllm.defaultllm.formulamplmpl.formulamplFitpicfitpicregpIndexpIndex.defaultpIndex.formulapIndexControlpIndexFitpIndexLocalpIndexThresholdplot.bhmplot.brmplot.coxpLRTplot.glmpLRTplot.llmplot.pIndexplot.resbootplot.residuals.brmplot.rmscbppicexppredict.coxpLRTprint.bhmprint.brmprint.coxpLRTprint.glmpLRTprint.llmprint.mplprint.picregprint.pIndexprint.resbootprint.rmscbprint.summary.bhmprint.summary.brmprolikFitqpicexpresbootresboot.defaultresboot.formularesbootCoxresiduals.brmrmscbrmscb.defaultrmscb.formularmsControlrpicexprpwexpsummary.bhmsummary.brmsummary.glmpLRTsummary.picregsummary.rmscbthm.fitthm.likx.cdf

Dependencies:clicodacpp11farverggplot2gluegridExtragtableisobandlabelinglatticelifecyclelplMASSMatrixmatrixStatsR6RColorBrewerrlangS7scalessurvivalvctrsviridisLitewithr

Readme and manuals

Help Manual

Help pageTopics
An R package for the biomarker threshold modelsbhm-package bhm-doc
Function to perform Adaptive Rejection Samplingarns ars rpwexp
Fitting Biomarker Threshold Modelsbhm bhm.default bhm.formula bhmFit bhmGibbs prolikFit summary.bhm thm.fit thm.lik x.cdf
Auxiliary function for bhm fittingbhmControl prolikControl
Fitting Biomarker Continuous Threshold Modelsbrm brm.default brm.formula residuals.brm summary.brm
Penalized Likelihood Ratio Test for a Biomarker Threshold Effect in the Cox Proportional Hazards ModelcoxpLRT coxpLRT.default coxpLRT.formula coxpLRTcvPredErr resbootCox
datasetdata gendat.glm gendat.surv
Creates a Kaplan-Meier plot with at risk tables belowggkm
Penalized likelihood ratio test for the generalized linear models.glmpLRT glmpLRT.default glmpLRT.formula plot.glmpLRT print.glmpLRT summary.glmpLRT
Fit an L-shape linear modelllm llm.default llm.formula plot.llm print.llm
Joint models for clustered data with binary and survival outcomes.mpl mpl.formula mplFit
Probability Index for Survival Time DifferencepIndex pIndex.default pIndex.formula pIndexFit pIndexLocal pIndexThreshold
Auxiliary function for pIndex fittingpIndexControl
Plot a fitted biomarker threhold modelplot.bhm plot.brm plot.coxpLRT plot.pIndex plot.resboot plot.residuals.brm
Predict Method for Model Fits in the 'bhm' packagepredict.coxpLRT
print a fitted object or a summary of fitted objectprint.bhm print.brm print.coxpLRT print.mpl print.picreg print.pIndex print.resboot print.summary.bhm print.summary.brm
Rresidual Bootstrap Test (RBT) for treatment-biomarker interactionresboot resboot.default resboot.formula
Fitting Restricted Mean Survival Time Models with a Continuous Biomarkerplot.rmscb print.rmscb rmscb rmscb.default rmscb.formula rmsControl summary.rmscb
The Piecewise Exponential Distributiondpicexp Hpicexp hpicexp picfit picreg ppicexp qpicexp rpicexp summary.picreg